Released in 2007, Hitman Trilogy includes PS2 editions the series' three most popular, cross-platform releases: Silent Assassin (2002), Contracts (2004) and Blood Money (2006).

Silent Assassin, IO Interactive's sequel to the PC's Codename 47, finds the Agent reluctantly pressed into service once again, after his close friend and personal confidant, a priest, is beaten and taken hostage by a gang of thugs. As a professional assassin handicapped with a conscience, players will pursue those responsible for this grievous error in judgment to the far corners of the world. After receiving their briefing, players can go about each mission as they see fit, for there is more than one way to complete objectives. Most of the locales are in the heart of enemy territory, requiring players to use stealth, caution, and careful planning to find a safe entrance and carry out the hit without arousing suspicions from enemy guards.